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Основной контент книги Cyclized Helical Peptides
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Volume 240 pages

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Cyclized Helical Peptides

Synthesis, Properties and Therapeutic Applications
authors
Zigang Li,
Hui Zhao
Читайте только на Литрес

The book cannot be downloaded as a file, but can be read in our app or online on the website.

$179.53

About the book

An important and timely guide to the progress being made on constrained helical peptides Constraint helical peptides have emerged as a solution to target previously undruggable protein-protein interactions, which feature large and complex surfaces. Cyclized Helical Peptides: Synthesis, Properties and Therapeutic Applications offers a review of the most current methodologies of constructing constrained helices. The authors noted experts on the topic include the information on the fundamental features of cyclized helical peptides and discuss their limitations. The book summarizes and explores the effects of chemical methods constructing helical peptides on helicity, binding affinity, cell penetration, and nonspecific toxicity. The book examines the therapeutic applications of the constraint helices and includes comparison with existing small molecule modulators or antibodies. Designed as a useful resource for both those outside and inside the field. Those new to the field will find a comprehensive introduction to cyclized helical peptide and those inside the field will find a deeper understanding of the topic. This important book: Offers a practical introduction to constrained helical peptides Includes all aspects of constrained helical peptides Includes information on the most recent methods that have emerged Presents a guide to help solve practical problems in the field Written for academics, pharmaceutical professional, Cyclized Helical Peptides is a comprehensive guide to the developments of constrained helical peptides.

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Age restriction:
0+
Volume:
240 p.
ISBN:
9783527343478
Total size:
8.6 МБ
Total number of pages:
240
Publisher:
Copyright holder:
John Wiley & Sons Limited
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