Читайте только на Литрес

The book cannot be downloaded as a file, but can be read in our app or online on the website.

Основной контент книги Fundamentals of Early Clinical Drug Development
Text PDF

Volume 341 page

0+

Fundamentals of Early Clinical Drug Development

From Synthesis Design to Formulation
Читайте только на Литрес

The book cannot be downloaded as a file, but can be read in our app or online on the website.

$192

About the book

An informative look at the intricacies of today's drug development process Once a discovery organization has identified a potential new drug candidate, it is the daunting task of synthetic organic chemists to identify the chemical process suitable for preparation of this compound in a highly regulated environment. Only through a multi-layered chemical process that takes into account such factors as safety, environmental considerations, freedom to operate and cost-effectiveness can researchers begin to refine the drug in terms of quality and yield. This book covers both recent advances in the design and synthesis of new drugs, as well as the myriad other issues facing a new drug candidate as it moves through the development process. Utilizing recent case studies, the authors provide valuable insights into the complexities of the process, from designing new synthetic methodologies and applying new automated techniques for finding optimal reaction conditions to selecting the final drug form and formulation. Both novice and active researchers will appreciate the inclusion of chapters on such diverse topics as: * Cross-coupling methods * Asymmetric synthesis * Automation * Chemical Engineering * Application of radioisotopes * Final form selection * Formulations * Intellectual property A wealth of real-world examples and contributions from leading process scientists, engineers, and related professionals make this book a valuable addition to the scientific literature.

Log in, to rate the book and leave a review
Book «Fundamentals of Early Clinical Drug Development» — read online on the website. Leave comments and reviews, vote for your favorites.
Age restriction:
0+
Release date on Litres:
20 August 2019
Volume:
341 p.
ISBN:
9780470043394
Total size:
5.2 МБ
Total number of pages:
341
Copyright holder:
John Wiley & Sons Limited
Text, audio format available
Average rating 4,7 based on 305 ratings
Audio
Average rating 4,2 based on 744 ratings
Text, audio format available
Average rating 4,8 based on 17 ratings
Text, audio format available
Average rating 4,9 based on 97 ratings
Text
Average rating 5 based on 23 ratings
Audio
Average rating 4,5 based on 4 ratings
Text, audio format available
Average rating 4,3 based on 50 ratings