Authored by the world's leading kinase experts, this is a comprehensive introduction to current knowledge and practice within this emerging field. <br> Following an overview of the major players and pathways that define the kinome, the major part of this work is devoted to current strategies of kinome investigation and manipulation. As such, kinase engineering, peptide substrate engineering, co-substrate design and kinase inhibitor design are discussed in detail, and their potential applications in kinome analysis and kinome-based pharmacotherapy are shown.<br> The result is a toolbox for every kinase researcher: By addressing and comparing current approaches to the study of kinase action, both novice and established researchers will benefit from the practical knowledge contained in this invaluable reference.<br>
Age restriction: 0+
Date added to LitRes: 20 June 2018
Size: 365 pp.
Total size: 8 MB
Total number of pages: 365
Page size:170 x 244 мм
Editors:Heinz-Bernhard Kraatz, Sanela Martic
Copyright:John Wiley & Sons Limited
Kinomics — read a free preview online. Leave comments and reviews, vote for your favorite.