Drug Discovery Toxicology

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From Target Assessment to Translational Biomarkers
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Book description

As a guide for pharmaceutical professionals to the issues and practices of drug discovery toxicology, this book integrates and reviews the strategy and application of tools and methods at each step of the drug discovery process.

• Guides researchers as to what drug safety experiments are both practical and useful• Covers a variety of key topics – safety lead optimization, in vitro-in vivo translation, organ toxicology, ADME, animal models, biomarkers, and –omics tools• Describes what experiments are possible and useful and offers a view into the future, indicating key areas to watch for new predictive methods• Features contributions from firsthand industry experience, giving readers insight into the strategy and execution of predictive toxicology practices

Detailed info
Age restriction:
0+
Date added to LitRes:
02 October 2018
Size:
601 pp.
ISBN:
9781119053323
Total size:
30 MB
Total number of pages:
601
Page size:
216 x 279 мм
Editors:
Andrew J. Olaharski, Brandon D. Jeffy, J. Eric McDuffie, Yvonne Will
Publisher:
Wiley
Copyright:
John Wiley & Sons Limited
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